human MYB shRNA silencing AAV

Cat. No: shAAV-216117

Availability: 4-5 weeks

Name: AAV-h-MYB-shRNA

This is an AAV expressing shRNA for silencing of Human MYB.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MYB
Gene Name: MYB proto-oncogene, transcription factor
Gene ID: 4602
Gene Synonyms: c-myb; c-myb_CDS; Cmyb; efg
ORF Size: 1923 bp
RefSeq#: NM_005375
Gene Description: MYB encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.654446
HGNC ID: HGNC:7545