human MARCKSL1 shRNA silencing AAV

Cat. No: shAAV-215032

Availability: 4-5 weeks

Name: AAV-h-MARCKSL1-shRNA

This is an AAV expressing shRNA for silencing of Human MARCKSL1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MARCKSL1
Gene Name: MARCKS like 1
Gene ID: 65108
Gene Synonyms: F52; MACMARCKS; MLP; MLP1; MRP
ORF Size: 588 bp
RefSeq#: NM_023009
Gene Description: MARCKSL1 encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10.
UniGene ID: Hs.707012
HGNC ID: HGNC:7142