mouse UBA6 shRNA silencing AAV

Cat. No: shAAV-275443

Availability: 4-5 weeks

Name: AAV-m-UBA6-shRNA

This is an AAV expressing shRNA for silencing of Mouse Uba6.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Uba6
Gene Name: ubiquitin-like modifier activating enzyme 6
Gene ID: 231380
Gene Synonyms: 4930542H01; 5730469D23Rik; AU021846; AW124799; E1-L2; Ube1l2
ORF Size: 3162 bp
RefSeq#: NM_172712
Gene Description: Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility.
UniGene ID: Mm.440954