human MAPKAPK2 shRNA silencing AAV

Cat. No: shAAV-214997

Availability: 4-5 weeks

Name: AAV-h-MAPKAPK2-shRNA

This is an AAV expressing shRNA for silencing of Human MAPKAPK2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MAPKAPK2
Gene Name: mitogen-activated protein kinase-activated protein kinase 2
Gene ID: 9261
Gene Synonyms: MAPKAP-K2; MK-2; MK2
ORF Size: 1203 bp
RefSeq#: NM_032960
Gene Description: MAPKAPK2 encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.
UniGene ID: Hs.713747
HGNC ID: HGNC:6887