human PCM1 shRNA silencing AAV

Cat. No: shAAV-218385

Availability: 4-5 weeks

Name: AAV-h-PCM1-shRNA

This is an AAV expressing shRNA for silencing of Human PCM1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PCM1
Gene Name: pericentriolar material 1
Gene ID: 5108
Gene Synonyms: PTC4; RET/PCM-1
ORF Size: 6051 bp
RefSeq#: NM_006197
Gene Description: PCM1 is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma.
UniGene ID: Hs.491148
HGNC ID: HGNC:8727