human MDH1 shRNA silencing AAV

Cat. No: shAAV-215214

Availability: 4-5 weeks

Name: AAV-h-MDH1-shRNA

This is an AAV expressing shRNA for silencing of Human MDH1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MDH1
Gene Name: malate dehydrogenase 1
Gene ID: 4190
Gene Synonyms: HEL-S-32; MDH-s; MDHA; MGC:1375; MOR2
ORF Size: 1005 bp
RefSeq#: NM_005917
Gene Description: Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
UniGene ID: Hs.526521
HGNC ID: HGNC:6970