human CTC1 shRNA silencing AAV

Cat. No: shAAV-229614

Availability: 4-5 weeks

Name: AAV-h-CTC1-shRNA

This is an AAV expressing shRNA for silencing of Human CTC1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CTC1
Gene Name: CST telomere replication complex component 1
Gene ID: 80169
Gene Synonyms: AAF-132; AAF132; C17orf68; CRMCC; tmp494178
ORF Size: 3654 bp
RefSeq#: NM_025099
Gene Description: CTC1 encodes a component of the CST complex. This complex plays an essential role in protecting telomeres from degradation. This protein also forms a heterodimer with the CST complex subunit STN1 to form the enzyme alpha accessory factor. This enzyme regulates DNA replication. Mutations in this gene are the cause of cerebroretinal microangiopathy with calcifications and cysts. Alternate splicing results in both coding and non-coding variants.
UniGene ID: Hs.156055
HGNC ID: HGNC:26169