human SYCP3 shRNA silencing AAV

Cat. No: shAAV-224798

Availability: 6-8 weeks

Name: AAV-h-SYCP3-shRNA

This is an AAV expressing shRNA for silencing of Human SYCP3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SYCP3
Gene Name: synaptonemal complex protein 3
Gene ID: 50511
Gene Synonyms: COR1; RPRGL4; SCP3; SPGF4
ORF Size: 711 bp
RefSeq#: NM_153694
Gene Description: SYCP3 encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.
UniGene ID: Hs.506504
HGNC ID: HGNC:18130