mouse IFI30 shRNA silencing AAV

Cat. No: shAAV-261880

Availability: 4-5 weeks

Name: AAV-m-IFI30-shRNA

This is an AAV expressing shRNA for silencing of Mouse Ifi30.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Ifi30
Gene Name: interferon gamma inducible protein 30
Gene ID: 65972
Gene Synonyms: GILT; IP30
ORF Size: 747 bp
RefSeq#: NM_023065
Gene Description: Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds (By similarity). Facilitates also MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or crosspresentation (By similarity).
UniGene ID: Mm.30241