human BBS12 shRNA silencing AAV

Cat. No: shAAV-201997

Availability: 6-8 weeks

Name: AAV-h-BBS12-shRNA

This is an AAV expressing shRNA for silencing of Human BBS12.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: BBS12
Gene Name: Bardet-Biedl syndrome 12
Gene ID: 166379
Gene Synonyms: C4orf24
ORF Size: 2133 bp
RefSeq#: NM_152618
Gene Description: BBS12 is part of a complex that is involved in membrane trafficking. The encoded protein is a molecular chaperone that aids in protein folding upon ATP hydrolysis. This protein also plays a role in adipocyte differentiation. Defects in this gene are a cause of Bardet-Biedl syndrome type 12. Two transcript variants encoding the same protein have been found for this gene.
UniGene ID: Hs.400698
HGNC ID: HGNC:26648