mouse SNRPC shRNA silencing AAV

Cat. No: shAAV-272760

Availability: 4-5 weeks

Name: AAV-m-SNRPC-shRNA

This is an AAV expressing shRNA for silencing of Mouse Snrpc.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Snrpc
Gene Name: U1 small nuclear ribonucleoprotein C
Gene ID: 20630
Gene Synonyms: Snrp1c; U1-C; U1C
ORF Size: 480 bp
RefSeq#: NM_011432
Gene Description: Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
UniGene ID: Mm.308514