human LILRA2 shRNA silencing AAV

Cat. No: shAAV-213926

Availability: 6-8 weeks

Name: AAV-h-LILRA2-shRNA

This is an AAV expressing shRNA for silencing of Human LILRA2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: LILRA2
Gene Name: leukocyte immunoglobulin like receptor A2
Gene ID: 11027
Gene Synonyms: CD85H; ILT1; LIR-7; LIR7
ORF Size: 1401 bp
RefSeq#: NM_006866
Gene Description: LILRA2 encodes a member of the leukocyte Ig-like receptor (LIR) family of immunoreceptors that are expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. The LIR family comprises of activating (subfamily A) and inhibitory (subfamily B) cell-surface receptors. The LIR encoded by this gene was shown to be an activating receptor for eosinophils that elicited the release of cytotoxic granule proteins, de novo lipid mediator generation, and cytokine release through vesicular transport. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.655593
HGNC ID: HGNC:6603