mouse TIMP1 shRNA silencing AAV

Cat. No: shAAV-274229

Availability: 4-5 weeks

Name: AAV-m-TIMP1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Timp1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Timp1
Gene Name: tissue inhibitor of metalloproteinase 1
Gene ID: 21857
Gene Synonyms: Clgi; EPA; Timp; TIMP-1; TPA-S1
ORF Size: 618 bp
RefSeq#: NM_011593
Gene Description: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14.
UniGene ID: Mm.8245