human ABCB6 shRNA silencing AAV

Cat. No: shAAV-200061

Availability: 4-5 weeks

Name: AAV-h-ABCB6-shRNA

This is an AAV expressing shRNA for silencing of Human ABCB6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ABCB6
Gene Name: ATP binding cassette subfamily B member 6 (Langereis blood group)
Gene ID: 10058
Gene Synonyms: ABC; ABC14; DUH3; LAN; MCOPCB7; MTABC3; PRP; PSHK2; umat
ORF Size: 2529 bp
RefSeq#: NM_005689
Gene Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
UniGene ID: Hs.107911
HGNC ID: HGNC:47