human RPS6KA1 shRNA silencing AAV

Cat. No: shAAV-221933

Availability: 4-5 weeks

Name: AAV-h-RPS6KA1-shRNA

This is an AAV expressing shRNA for silencing of Human RPS6KA1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RPS6KA1
Gene Name: ribosomal protein S6 kinase A1
Gene ID: 6195
Gene Synonyms: HU-1; MAPKAPK1A; p90Rsk; RSK; RSK1
ORF Size: 2208 bp
RefSeq#: NM_002953
Gene Description: RPS6KA1 encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
UniGene ID: Hs.149957
HGNC ID: HGNC:10430