human LRRN2 shRNA silencing AAV

Cat. No: shAAV-214605

Availability: 6-8 weeks

Name: AAV-h-LRRN2-shRNA

This is an AAV expressing shRNA for silencing of Human LRRN2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: LRRN2
Gene Name: leucine rich repeat neuronal 2
Gene ID: 10446
Gene Synonyms: FIGLER7; GAC1; LRANK1; LRRN5
ORF Size: 2142 bp
RefSeq#: NM_006338
Gene Description: LRRN2 belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
UniGene ID: Hs.26312
HGNC ID: HGNC:16914