human KCNIP1 shRNA silencing AAV

Cat. No: shAAV-212704

Availability: 6-8 weeks

Name: AAV-h-KCNIP1-shRNA

This is an AAV expressing shRNA for silencing of Human KCNIP1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: KCNIP1
Gene Name: potassium voltage-gated channel interacting protein 1
Gene ID: 30820
Gene Synonyms: KCHIP1; VABP
ORF Size: 651 bp
RefSeq#: NM_014592
Gene Description: KCNIP1 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Alternative splicing results in multiple transcript variant encoding different isoforms.
UniGene ID: Hs.484111
HGNC ID: HGNC:15521