human PFDN5 shRNA silencing AAV

Cat. No: shAAV-218663

Availability: 4-5 weeks

Name: AAV-h-PFDN5-shRNA

This is an AAV expressing shRNA for silencing of Human PFDN5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PFDN5
Gene Name: prefoldin subunit 5
Gene ID: 5204
Gene Synonyms: MM-1; MM1; PFD5
ORF Size: 465 bp
RefSeq#: NM_002624
Gene Description: PFDN5 encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.
UniGene ID: Hs.655327
HGNC ID: HGNC:8869