human ARSG shRNA silencing AAV

Cat. No: shAAV-201488

Availability: 6-8 weeks

Name: AAV-h-ARSG-shRNA

This is an AAV expressing shRNA for silencing of Human ARSG.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ARSG
Gene Name: arylsulfatase G
Gene ID: 22901
ORF Size: 1578 bp
RefSeq#: NM_014960
Gene Description: ARSG belongs to the sulfatase enzyme family. Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This protein displays arylsulfatase activity at acidic pH, as is typical of lysosomal sulfatases, and has been shown to localize in the lysosomes. Alternatively spliced transcript variants have been found for this gene.
UniGene ID: Hs.437249
HGNC ID: HGNC:24102