human EIF2S2 shRNA silencing AAV

Cat. No: shAAV-207727

Availability: 4-5 weeks

Name: AAV-h-EIF2S2-shRNA

This is an AAV expressing shRNA for silencing of Human EIF2S2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: EIF2S2
Gene Name: eukaryotic translation initiation factor 2 subunit beta
Gene ID: 8894
Gene Synonyms: eIF-2-beta; EIF2; EIF2B; EIF2beta; PPP1R67
ORF Size: 645 bp
RefSeq#: NM_003908
Gene Description: Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation.
UniGene ID: Hs.429180
HGNC ID: HGNC:3266