human MAD1L1 shRNA silencing AAV

Cat. No: shAAV-214774

Availability: 4-5 weeks

Name: AAV-h-MAD1L1-shRNA

This is an AAV expressing shRNA for silencing of Human MAD1L1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MAD1L1
Gene Name: MAD1 mitotic arrest deficient like 1
Gene ID: 8379
Gene Synonyms: MAD1; PIG9; TP53I9; TXBP181
ORF Size: 2157 bp
RefSeq#: NM_003550
Gene Description: MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.
UniGene ID: Hs.654838
HGNC ID: HGNC:6762