human CANX shRNA silencing AAV

Cat. No: shAAV-204029

Availability: 4-5 weeks

Name: AAV-h-CANX-shRNA

This is an AAV expressing shRNA for silencing of Human CANX.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CANX
Gene Name: calnexin
Gene ID: 821
Gene Synonyms: CNX; IP90; P90
ORF Size: 1779 bp
RefSeq#: NM_001746
Gene Description: CANX encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
UniGene ID: Hs.699155
HGNC ID: HGNC:1473