human HAL shRNA silencing AAV

Cat. No: shAAV-210769

Availability: 6-8 weeks

Name: AAV-h-HAL-shRNA

This is an AAV expressing shRNA for silencing of Human HAL.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HAL
Gene Name: histidine ammonia-lyase
Gene ID: 3034
Gene Synonyms: HIS; HSTD
ORF Size: 1974 bp
RefSeq#: NM_002108
Gene Description: Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids. Several transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.190783
HGNC ID: HGNC:4806