human GRIA1 shRNA silencing AAV

Cat. No: shAAV-210505

Availability: 4-5 weeks

Name: AAV-h-GRIA1-shRNA

This is an AAV expressing shRNA for silencing of Human GRIA1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GRIA1
Gene Name: glutamate ionotropic receptor AMPA type subunit 1
Gene ID: 2890
Gene Synonyms: GluA1; GLUH1; GLUR1; GLURA; HBGR1
ORF Size: 2721 bp
RefSeq#: NM_000827
Gene Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.519693
HGNC ID: HGNC:4571