human ANAPC7 shRNA silencing AAV

Cat. No: shAAV-201464

Availability: 4-5 weeks

Name: AAV-h-ANAPC7-shRNA

This is an AAV expressing shRNA for silencing of Human ANAPC7.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ANAPC7
Gene Name: anaphase promoting complex subunit 7
Gene ID: 51434
Gene Synonyms: APC7
ORF Size: 1698 bp
RefSeq#: NM_016238
Gene Description: ANAPC7 encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.524741
HGNC ID: HGNC:17380