human PTP4A1 shRNA silencing AAV

Cat. No: shAAV-220296

Availability: 4-5 weeks

Name: AAV-h-PTP4A1-shRNA

This is an AAV expressing shRNA for silencing of Human PTP4A1.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PTP4A1
Gene Name: protein tyrosine phosphatase type IVA, member 1
Gene ID: 7803
Gene Synonyms: HH72; PRL-1; PRL1; PTP(CAAX1); PTPCAAX1
ORF Size: 522 bp
RefSeq#: NM_003463
Gene Description: PTP4A1 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.
UniGene ID: Hs.227777
HGNC ID: HGNC:9634