human PCOLCE shRNA silencing AAV

Cat. No: shAAV-218399

Availability: 4-5 weeks

Name: AAV-h-PCOLCE-shRNA

This is an AAV expressing shRNA for silencing of Human PCOLCE.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PCOLCE
Gene Name: procollagen C-endopeptidase enhancer
Gene ID: 5118
Gene Synonyms: PCPE; PCPE-1; PCPE1
ORF Size: 1350 bp
RefSeq#: NM_002593
Gene Description: Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity.
UniGene ID: Hs.202097
HGNC ID: HGNC:8738