human FOXO3 shRNA silencing AAV

Cat. No: shAAV-209273

Availability: 4-5 weeks

Name: AAV-h-FOXO3-shRNA

This is an AAV expressing shRNA for silencing of Human FOXO3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FOXO3
Gene Name: forkhead box O3
Gene ID: 2309
Gene Synonyms: AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A
ORF Size: 2022 bp
RefSeq#: NM_001455
Gene Description: FOXO3 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
UniGene ID: Hs.220950
HGNC ID: HGNC:3821