human DBN1 shRNA silencing AAV

Cat. No: shAAV-206622

Availability: 4-5 weeks

Name: AAV-h-DBN1-shRNA

This is an AAV expressing shRNA for silencing of Human DBN1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: DBN1
Gene Name: drebrin 1
Gene ID: 1627
Gene Synonyms: D0S117E
ORF Size: 1950 bp
RefSeq#: NM_004395
Gene Description: DBN1 is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
UniGene ID: Hs.130316
HGNC ID: HGNC:2695