human CHRM5 shRNA silencing AAV

Cat. No: shAAV-229051

Availability: 6-8 weeks

Name: AAV-h-CHRM5-shRNA

This is an AAV expressing shRNA for silencing of Human CHRM5.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CHRM5
Gene Name: cholinergic receptor muscarinic 5
Gene ID: 1133
Gene Synonyms: HM5
ORF Size: 1599 bp
RefSeq#: NM_012125
Gene Description: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels.
UniGene ID: Hs.584747
HGNC ID: HGNC:1954