human SNAI2 shRNA silencing AAV

Cat. No: shAAV-223804

Availability: 4-5 weeks

Name: AAV-h-SNAI2-shRNA

This is an AAV expressing shRNA for silencing of Human SNAI2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SNAI2
Gene Name: snail family transcriptional repressor 2
Gene ID: 6591
Gene Synonyms: SLUG; SLUGH1; SNAIL2; WS2D
ORF Size: 807 bp
RefSeq#: NM_003068
Gene Description: SNAI2 encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.
UniGene ID: Hs.360174
HGNC ID: HGNC:11094