mouse CAMK1D shRNA silencing AAV

Cat. No: shAAV-254437

Availability: 6-8 weeks

Name: AAV-m-CAMK1D-shRNA

This is an AAV expressing shRNA for silencing of Mouse Camk1d.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Camk1d
Gene Name: calcium/calmodulin-dependent protein kinase ID
Gene ID: 227541
Gene Synonyms: A630059D12Rik; CaMKIdelta; CKLiK; E030025C11Rik; mCKLiK
ORF Size: 1158 bp
RefSeq#: NM_177343
Gene Description: Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Phosphorylates the transcription activator CREB1 on 'Ser-133' in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta.
UniGene ID: Mm.191949