mouse NKX3-1 shRNA silencing AAV

Cat. No: shAAV-265823

Availability: 4-5 weeks

Name: AAV-m-NKX3-1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Nkx3-1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Nkx3-1
Gene Name: NK-3 transcription factor, locus 1 (Drosophila)
Gene ID: 18095
Gene Synonyms: bagpipe; Bax; Nkx-3.1; NKX3.1; NKX3A
ORF Size: 714 bp
RefSeq#: NM_010921
Gene Description: Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
UniGene ID: Mm.3520