mouse MYO5B shRNA silencing AAV

Cat. No: shAAV-265339

Availability: 6-8 weeks

Name: AAV-m-MYO5B-shRNA

This is an AAV expressing shRNA for silencing of Mouse Myo5b.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Myo5b
Gene Name: myosin VB
Gene ID: 17919
Gene Synonyms: AI661750; mKIAA1119
ORF Size: 5457 bp
RefSeq#: NM_201600
Gene Description: MYO5B may be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis (By similarity).
UniGene ID: Mm.260098

Product	Cat No.
Ad-m-MYO5B	ADV-265339
Ad-m-MYO5B-shRNA	shADV-265339