mouse AIF1 shRNA silencing AAV

Cat. No: shAAV-252365

Availability: 6-8 weeks

Name: AAV-m-AIF1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Aif1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Aif1
Gene Name: allograft inflammatory factor 1
Gene ID: 11629
Gene Synonyms: AI607846; AIF-1; D17H6S50E; G1; Iba1
ORF Size: 444 bp
RefSeq#: NM_019467
Gene Description: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
UniGene ID: Mm.10747