mouse CFB shRNA silencing AAV

Cat. No: shAAV-255325

Availability: 6-8 weeks

Name: AAV-m-CFB-shRNA

This is an AAV expressing shRNA for silencing of Mouse Cfb.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Cfb
Gene Name: complement factor B
Gene ID: 14962
Gene Synonyms: AI195813; AI255840; B; Bf; C2; Fb; H2-Bf
ORF Size: 2286 bp
RefSeq#: NM_008198
Gene Description: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
UniGene ID: Mm.653