human FBXL13 shRNA silencing AAV

Cat. No: shAAV-208748

Availability: 6-8 weeks

Name: AAV-h-FBXL13-shRNA

This is an AAV expressing shRNA for silencing of Human FBXL13.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: FBXL13
Gene Name: F-box and leucine rich repeat protein 13
Gene ID: 222235
Gene Synonyms: DRC6; Fbl13
ORF Size: 2124 bp
RefSeq#: NM_145032
Gene Description: Members of the F-box protein family, such as FBXL13, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.660029
HGNC ID: HGNC:21658