human PSMD1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-220144
Availability:
4-5 weeks
Name:
AAV-h-PSMD1-shRNA
This is an AAV expressing shRNA for silencing of Human PSMD1.
Request a Quote
Please enter your email address and we'll be in touch with more information:
Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PSMD1
- Gene Name
- proteasome 26S subunit, non-ATPase 1
- Gene ID
- 5707
- Gene Synonyms
- P112; Rpn2; S1
- ORF Size
- 2862 bp
- RefSeq#
- NM_002807
- Gene Description
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.
- UniGene ID
- Hs.3887
- HGNC ID
- HGNC:9554
Related Products
Product | Cat No. |
---|---|
AAV-h-PSMD1 | AAV-220144 |
AAV-m-PSMD1 | AAV-269654 |
Ad-h-PSMD1 | ADV-220144 |
Ad-m-PSMD1 | ADV-269654 |
AAV-m-PSMD1-shRNA | shAAV-269654 |
Ad-h-PSMD1-shRNA | shADV-220144 |
Ad-m-PSMD1-shRNA | shADV-269654 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
Vector Biolabs
293 Great Valley Parkway
Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
Toll-free (US Only): 877-BIO-LABS
Fax: +1 215-525-1112
Privacy Policy