human HSP90B1 shRNA silencing AAV

Cat. No: shAAV-211620

Availability: 4-5 weeks

Name: AAV-h-HSP90B1-shRNA

This is an AAV expressing shRNA for silencing of Human HSP90B1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: HSP90B1
Gene Name: heat shock protein 90 beta family member 1
Gene ID: 7184
Gene Synonyms: ECGP; GP96; GRP94; HEL-S-125m; HEL35; TRA1
ORF Size: 2412 bp
RefSeq#: NM_003299
Gene Description: HSP90B1 encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.
UniGene ID: Hs.192374
HGNC ID: HGNC:12028