human ATP7A shRNA silencing AAV

Cat. No: shAAV-201778

Availability: 4-5 weeks

Name: AAV-h-ATP7A-shRNA

This is an AAV expressing shRNA for silencing of Human ATP7A.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ATP7A
Gene Name: ATPase copper transporting alpha
Gene ID: 538
Gene Synonyms: DSMAX; MK; MNK; SMAX3
ORF Size: 4500 bp
RefSeq#: NM_000052
Gene Description: ATP7A encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans-Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked cutis laxa, and occipital horn syndrome.
UniGene ID: Hs.496414
HGNC ID: HGNC:869