human UBE2R2 shRNA silencing AAV

Cat. No: shAAV-227030

Availability: 4-5 weeks

Name: AAV-h-UBE2R2-shRNA

This is an AAV expressing shRNA for silencing of Human UBE2R2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: UBE2R2
Gene Name: ubiquitin conjugating enzyme E2 R2
Gene ID: 54926
Gene Synonyms: CDC34B; E2-CDC34B; UBC3B
ORF Size: 717 bp
RefSeq#: NM_017811
Gene Description: Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.
UniGene ID: Hs.718444
HGNC ID: HGNC:19907