human AMD1 shRNA silencing AAV

Cat. No: shAAV-200837

Availability: 4-5 weeks

Name: AAV-h-AMD1-shRNA

This is an AAV expressing shRNA for silencing of Human AMD1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: AMD1
Gene Name: adenosylmethionine decarboxylase 1
Gene ID: 262
Gene Synonyms: ADOMETDC; AMD; SAMDC
ORF Size: 1005 bp
RefSeq#: NM_001634
Gene Description: AMD1 encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y.
UniGene ID: Hs.159118
HGNC ID: HGNC:457