human GTF2IRD1 shRNA silencing AAV

Cat. No: shAAV-210650

Availability: 4-5 weeks

Name: AAV-h-GTF2IRD1-shRNA

This is an AAV expressing shRNA for silencing of Human GTF2IRD1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GTF2IRD1
Gene Name: GTF2I repeat domain containing 1
Gene ID: 9569
Gene Synonyms: BEN; CREAM1; GTF3; hMusTRD1alpha1; MUSTRD1; RBAP2; WBS; WBSCR11; WBSCR12
ORF Size: 2880 bp
RefSeq#: NM_005685
Gene Description: GTF2IRD1 contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.647056
HGNC ID: HGNC:4661