mouse TJP1 shRNA silencing AAV

Cat. No: shAAV-274245

Availability: 4-5 weeks

Name: AAV-m-TJP1-shRNA

This is an AAV expressing shRNA for silencing of Mouse Tjp1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Tjp1
Gene Name: tight junction protein 1
Gene ID: 21872
Gene Synonyms: ZO1
ORF Size: 5058 bp
RefSeq#: NM_009386
Gene Description: The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
UniGene ID: Mm.4342