human GRB7 shRNA silencing AAV

Cat. No: shAAV-210490

Availability: 6-8 weeks

Name: AAV-h-GRB7-shRNA

This is an AAV expressing shRNA for silencing of Human GRB7.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: GRB7
Gene Name: growth factor receptor bound protein 7
Gene ID: 2886
ORF Size: 1599 bp
RefSeq#: NM_005310
Gene Description: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Several transcript variants encoding two different isoforms have been found for this gene.
UniGene ID: Hs.86859
HGNC ID: HGNC:4567