human CAPN1 shRNA silencing AAV

Cat. No: shAAV-204036

Availability: 6-8 weeks

Name: AAV-h-CAPN1-shRNA

This is an AAV expressing shRNA for silencing of Human CAPN1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CAPN1
Gene Name: calpain 1
Gene ID: 823
Gene Synonyms: CANP; CANP1; CANPL1; muCANP; muCL; SPG76
ORF Size: 2145 bp
RefSeq#: NM_005186
Gene Description: The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.
UniGene ID: Hs.502842
HGNC ID: HGNC:1476