human RGS9BP shRNA silencing AAV

Cat. No: shAAV-221142

Availability: 6-8 weeks

Name: AAV-h-RGS9BP-shRNA

This is an AAV expressing shRNA for silencing of Human RGS9BP.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RGS9BP
Gene Name: regulator of G-protein signaling 9 binding protein
Gene ID: 388531
Gene Synonyms: PERRS; R9AP; RGS9
ORF Size: 708 bp
RefSeq#: NM_207391
Gene Description: RGS9BP functions as a regulator of G protein-coupled receptor signaling in phototransduction. Studies in bovine and mouse show that this gene is expressed only in the retina, and is localized in the rod outer segment membranes. This protein is associated with a heterotetrameric complex, specifically interacting with the regulator of G-protein signaling 9, and appears to function as the membrane anchor for the other largely soluble interacting partners. Mutations in this gene are associated with prolonged electroretinal response suppression (PERRS), also known as bradyopsia.
UniGene ID: Hs.528491
HGNC ID: HGNC:30304