human CRYL1 shRNA silencing AAV

Cat. No: shAAV-206079

Availability: 4-5 weeks

Name: AAV-h-CRYL1-shRNA

This is an AAV expressing shRNA for silencing of Human CRYL1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: CRYL1
Gene Name: crystallin lambda 1
Gene ID: 51084
Gene Synonyms: GDH; HEL30; lambda-CRY
ORF Size: 894 bp
RefSeq#: NM_015974
Gene Description: The uronate cycle functions as an alternative glucose metabolic pathway, accounting for about 5% of daily glucose catabolism. The product of this gene catalyzes the dehydrogenation of L-gulonate into dehydro-L-gulonate in the uronate cycle. The enzyme requires NAD(H) as a coenzyme, and is inhibited by inorganic phosphate. A similar gene in the rabbit is thought to serve a structural role in the lens of the eye.
UniGene ID: Hs.370703
HGNC ID: HGNC:18246