mouse RAC2 shRNA silencing AAV

Cat. No: shAAV-270047

Availability: 6-8 weeks

Name: AAV-m-RAC2-shRNA

This is an AAV expressing shRNA for silencing of Mouse Rac2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Rac2
Gene Name: RAS-related C3 botulinum substrate 2
Gene ID: 19354
Gene Synonyms: AI323801; AI452260
ORF Size: 579 bp
RefSeq#: NM_009008
Gene Description: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
UniGene ID: Mm.1972