human PTK6 shRNA silencing AAV

Cat. No: shAAV-220273

Availability: 4-5 weeks

Name: AAV-h-PTK6-shRNA

This is an AAV expressing shRNA for silencing of Human PTK6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PTK6
Gene Name: protein tyrosine kinase 6
Gene ID: 5753
Gene Synonyms: BRK
ORF Size: 1356 bp
RefSeq#: NM_005975
Gene Description: PTK6 is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.51133
HGNC ID: HGNC:9617